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Establishment of quantitative RNAi-based forward genetics in Entamoeba histolytica and identification of genes required for growth
While Entamoeba histolytica remains a globally important pathogen, it is dramatically understudied. The tractability of E. histolytica has historically been limited, which is largely due to challenging features of its genome. To enable forward genetics, we constructed and validated the first genome-...
Autores principales: | Bettadapur, Akhila, Hunter, Samuel S., Suleiman, Rene L., Ruyechan, Maura C., Huang, Wesley, Barbieri, Charles G., Miller, Hannah W., Tam, Tammie S. Y., Settles, Matthew L., Ralston, Katherine S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716031/ https://www.ncbi.nlm.nih.gov/pubmed/34843592 http://dx.doi.org/10.1371/journal.ppat.1010088 |
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