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Statistical tests for intra-tumour clonal co-occurrence and exclusivity

Tumour progression is an evolutionary process in which different clones evolve over time, leading to intra-tumour heterogeneity. Interactions between clones can affect tumour evolution and hence disease progression and treatment outcome. Intra-tumoural pairs of mutations that are overrepresented in...

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Detalles Bibliográficos
Autores principales: Kuipers, Jack, Moore, Ariane L., Jahn, Katharina, Schraml, Peter, Wang, Feng, Morita, Kiyomi, Futreal, P. Andrew, Takahashi, Koichi, Beisel, Christian, Moch, Holger, Beerenwinkel, Niko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716063/
https://www.ncbi.nlm.nih.gov/pubmed/34910733
http://dx.doi.org/10.1371/journal.pcbi.1009036