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Statistical tests for intra-tumour clonal co-occurrence and exclusivity
Tumour progression is an evolutionary process in which different clones evolve over time, leading to intra-tumour heterogeneity. Interactions between clones can affect tumour evolution and hence disease progression and treatment outcome. Intra-tumoural pairs of mutations that are overrepresented in...
Autores principales: | Kuipers, Jack, Moore, Ariane L., Jahn, Katharina, Schraml, Peter, Wang, Feng, Morita, Kiyomi, Futreal, P. Andrew, Takahashi, Koichi, Beisel, Christian, Moch, Holger, Beerenwinkel, Niko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716063/ https://www.ncbi.nlm.nih.gov/pubmed/34910733 http://dx.doi.org/10.1371/journal.pcbi.1009036 |
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