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RNA sequencing and proteomic profiling reveal different alterations by dietary methylmercury in the hippocampal transcriptome and proteome in BALB/c mice

Methylmercury (MeHg) is a highly neurotoxic form of mercury (Hg) present in seafood. Here, we recorded and compared proteomic and transcriptomic changes in hippocampus of male BALB/c mice exposed to two doses of MeHg. Mice were fed diets spiked with 0.28 mg MeHg kg(–1), 5 mg MeHg kg(–1), or an unspi...

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Detalles Bibliográficos
Autores principales: Mellingen, Ragnhild Marie, Myrmel, Lene Secher, Lie, Kai Kristoffer, Rasinger, Josef Daniel, Madsen, Lise, Nøstbakken, Ole Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716076/
https://www.ncbi.nlm.nih.gov/pubmed/33890672
http://dx.doi.org/10.1093/mtomcs/mfab022