VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction

Lung ischemia reperfusion injury (LIRI) is a complex pathophysiological process with high morbidity and mortality. An important pathophysiological characteristic of LIRI is endothelial barrier dysfunction, although the mechanism involved in this process remains unclear. VX765, a specific caspase-1 i...

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Detalles Bibliográficos
Autores principales: Wu, Siyi, Li, Zhao, Ye, Mengling, Liu, Chunxia, Liu, Hao, He, Xiaojing, Qin, Yi, Liang, Fangte, Pan, Linghui, Lin, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716216/
https://www.ncbi.nlm.nih.gov/pubmed/34977239
http://dx.doi.org/10.1155/2021/4525988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716216/
https://www.ncbi.nlm.nih.gov/pubmed/34977239
http://dx.doi.org/10.1155/2021/4525988

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