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VX765, a Specific Caspase-1 Inhibitor, Alleviates Lung Ischemia Reperfusion Injury by Suppressing Endothelial Pyroptosis and Barrier Dysfunction

Lung ischemia reperfusion injury (LIRI) is a complex pathophysiological process with high morbidity and mortality. An important pathophysiological characteristic of LIRI is endothelial barrier dysfunction, although the mechanism involved in this process remains unclear. VX765, a specific caspase-1 i...

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Detalles Bibliográficos
Autores principales:	Wu, Siyi, Li, Zhao, Ye, Mengling, Liu, Chunxia, Liu, Hao, He, Xiaojing, Qin, Yi, Liang, Fangte, Pan, Linghui, Lin, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716216/ https://www.ncbi.nlm.nih.gov/pubmed/34977239 http://dx.doi.org/10.1155/2021/4525988

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