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Low Dose Pig Anti-Influenza Virus Monoclonal Antibodies Reduce Lung Pathology but Do Not Prevent Virus Shedding

We have established the pig, a large natural host animal for influenza, with many physiological similarities to humans, as a robust model for testing the therapeutic potential of monoclonal antibodies (mAbs). In this study we demonstrated that prophylactic intravenous administration of 15 mg/kg of p...

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Detalles Bibliográficos
Autores principales: Paudyal, Basudev, McNee, Adam, Rijal, Pramila, Carr, B. Veronica, Nunez, Alejandro, McCauley, John, Daniels, Rodney S., Townsend, Alain R., Hammond, John A., Tchilian, Elma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716435/
https://www.ncbi.nlm.nih.gov/pubmed/34975888
http://dx.doi.org/10.3389/fimmu.2021.790918