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Low Dose Pig Anti-Influenza Virus Monoclonal Antibodies Reduce Lung Pathology but Do Not Prevent Virus Shedding
We have established the pig, a large natural host animal for influenza, with many physiological similarities to humans, as a robust model for testing the therapeutic potential of monoclonal antibodies (mAbs). In this study we demonstrated that prophylactic intravenous administration of 15 mg/kg of p...
Autores principales: | Paudyal, Basudev, McNee, Adam, Rijal, Pramila, Carr, B. Veronica, Nunez, Alejandro, McCauley, John, Daniels, Rodney S., Townsend, Alain R., Hammond, John A., Tchilian, Elma |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716435/ https://www.ncbi.nlm.nih.gov/pubmed/34975888 http://dx.doi.org/10.3389/fimmu.2021.790918 |
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