DNA Damage and Repair Deficiency in ALS/FTD-Associated Neurodegeneration: From Molecular Mechanisms to Therapeutic Implication

Emerging studies reveal that neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), are commonly linked to DNA damage accumulation and repair deficiency. Neurons are particularly vulnerable to DNA damage due to their high metabolic activity, rel...

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Detalles Bibliográficos
Autores principales: Wang, Haibo, Kodavati, Manohar, Britz, Gavin W., Hegde, Muralidhar L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716463/
https://www.ncbi.nlm.nih.gov/pubmed/34975400
http://dx.doi.org/10.3389/fnmol.2021.784361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716463/
https://www.ncbi.nlm.nih.gov/pubmed/34975400
http://dx.doi.org/10.3389/fnmol.2021.784361

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