Targeting Mitochondrial Metabolism and RNA Polymerase POLRMT to Overcome Multidrug Resistance in Cancer

Clinically, the prognosis of tumor therapy is fundamentally affected by multidrug resistance (MDR), which is primarily a result of enhanced drug efflux mediated by channels in the membrane that reduce drug accumulation in tumor cells. How to restore the sensitivity of tumor cells to chemotherapy is...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Hui-Jing, Xiao, Guan-Li, Zhao, Yu-Ying, Wang, Xin-Xin, Lan, Rongfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716502/
https://www.ncbi.nlm.nih.gov/pubmed/34976949
http://dx.doi.org/10.3389/fchem.2021.775226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716502/
https://www.ncbi.nlm.nih.gov/pubmed/34976949
http://dx.doi.org/10.3389/fchem.2021.775226

Ejemplares similares