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Targeting Mitochondrial Metabolism and RNA Polymerase POLRMT to Overcome Multidrug Resistance in Cancer

Clinically, the prognosis of tumor therapy is fundamentally affected by multidrug resistance (MDR), which is primarily a result of enhanced drug efflux mediated by channels in the membrane that reduce drug accumulation in tumor cells. How to restore the sensitivity of tumor cells to chemotherapy is...

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Detalles Bibliográficos
Autores principales:	Yu, Hui-Jing, Xiao, Guan-Li, Zhao, Yu-Ying, Wang, Xin-Xin, Lan, Rongfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716502/ https://www.ncbi.nlm.nih.gov/pubmed/34976949 http://dx.doi.org/10.3389/fchem.2021.775226

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