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Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients with systemic lupus erythematosus

SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting disease course. Although the etiology and mechanisms of SLE flares remain elusive, Epstein-Barr virus (EBV) reactivation is implicated in SLE pathogenesis. This study examined the relationships between se...

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Detalles Bibliográficos
Autores principales: Wood, Rebecca A., Guthridge, Lauren, Thurmond, Emma, Guthridge, Carla J., Kheir, Joseph M., Bourn, Rebecka L., Wagner, Catriona A., Chen, Hua, DeJager, Wade, Macwana, Susan R., Kamp, Stan, Lu, Rufei, Arriens, Cristina, Chakravarty, Eliza F., Thanou, Aikaterini, Merrill, Joan T., Guthridge, Joel M., James, Judith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716608/
https://www.ncbi.nlm.nih.gov/pubmed/35005588
http://dx.doi.org/10.1016/j.jtauto.2021.100117