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The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway

Multiple cross-sectional and longitudinal studies have shown that serum levels of the chemokine ligand 2 (CCL-2) are associated with type 1 diabetes (T1D), although the direction of effect differs. We assessed CCL-2 serum levels in a longitudinal cohort to clarify this association, combined with gen...

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Detalles Bibliográficos
Autores principales: Tran, Paul MH., Purohit, Sharad, Kim, Eileen, bin Satter, Khaled, Hopkins, Diane, Waugh, Kathleen, Dong, Fran, Onengut-Gumuscu, Suna, Rich, Stephen S., Rewers, Marian, She, Jin-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716652/
https://www.ncbi.nlm.nih.gov/pubmed/35005592
http://dx.doi.org/10.1016/j.jtauto.2021.100127