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The 3p21.31 genetic locus promotes progression to type 1 diabetes through the CCR2/CCL2 pathway
Multiple cross-sectional and longitudinal studies have shown that serum levels of the chemokine ligand 2 (CCL-2) are associated with type 1 diabetes (T1D), although the direction of effect differs. We assessed CCL-2 serum levels in a longitudinal cohort to clarify this association, combined with gen...
Autores principales: | Tran, Paul MH., Purohit, Sharad, Kim, Eileen, bin Satter, Khaled, Hopkins, Diane, Waugh, Kathleen, Dong, Fran, Onengut-Gumuscu, Suna, Rich, Stephen S., Rewers, Marian, She, Jin-Xiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716652/ https://www.ncbi.nlm.nih.gov/pubmed/35005592 http://dx.doi.org/10.1016/j.jtauto.2021.100127 |
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