Programmed Cell Death Protein 1 Blockade Reduces Glycogen Synthase Kinase 3β Activity and Tau Hyperphosphorylation in Alzheimer’s Disease Mouse Models

Alzheimer’s disease (AD) is a central nervous system degenerative disease, with no effective treatment to date. Administration of immune checkpoint inhibitors significantly reduces neuronal damage and tau hyperphosphorylation in AD, but the specific mechanism is unclear. Here, we found that programm...

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Detalles Bibliográficos
Autores principales: Zou, Yulian, Gan, Chen-Ling, Xin, Zhiming, Zhang, Hai-Tao, Zhang, Qi, Lee, Tae Ho, Pan, Xiaodong, Chen, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716757/
https://www.ncbi.nlm.nih.gov/pubmed/34977020
http://dx.doi.org/10.3389/fcell.2021.769229

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716757/
https://www.ncbi.nlm.nih.gov/pubmed/34977020
http://dx.doi.org/10.3389/fcell.2021.769229

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