Inferring Homologous Recombination Deficiency of Ovarian Cancer From the Landscape of Copy Number Variation at Subchromosomal and Genetic Resolutions

BACKGROUND: Homologous recombination deficiency (HRD) is characterized by overall genomic instability and has emerged as an indispensable therapeutic target across various tumor types, particularly in ovarian cancer (OV). Unfortunately, current detection assays are far from perfect for identifying e...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Ma, Si-Cong, Tan, Jia-Le, Wang, Jian, Bai, Xue, Dong, Zhong-Yi, Zhang, Qing-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716765/
https://www.ncbi.nlm.nih.gov/pubmed/34976815
http://dx.doi.org/10.3389/fonc.2021.772604

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716765/
https://www.ncbi.nlm.nih.gov/pubmed/34976815
http://dx.doi.org/10.3389/fonc.2021.772604

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