The RUNX1b Isoform Defines Hemogenic Competency in Developing Human Endothelial Cells

The transcription factor RUNX1 is a master regulator of blood cell specification. During embryogenesis, hematopoietic progenitors are initially generated from hemogenic endothelium through an endothelium-to-hematopoietic transition controlled by RUNX1. Several studies have dissected the expression p...

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Detalles Bibliográficos
Autores principales: Menegatti, Sara, Potts, Bethany, Garcia-Alegria, Eva, Paredes, Roberto, Lie-A-Ling, Michael, Lacaud, Georges, Kouskoff, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716778/
https://www.ncbi.nlm.nih.gov/pubmed/34977046
http://dx.doi.org/10.3389/fcell.2021.812639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716778/
https://www.ncbi.nlm.nih.gov/pubmed/34977046
http://dx.doi.org/10.3389/fcell.2021.812639

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