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The RUNX1b Isoform Defines Hemogenic Competency in Developing Human Endothelial Cells
The transcription factor RUNX1 is a master regulator of blood cell specification. During embryogenesis, hematopoietic progenitors are initially generated from hemogenic endothelium through an endothelium-to-hematopoietic transition controlled by RUNX1. Several studies have dissected the expression p...
Autores principales: | Menegatti, Sara, Potts, Bethany, Garcia-Alegria, Eva, Paredes, Roberto, Lie-A-Ling, Michael, Lacaud, Georges, Kouskoff, Valerie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716778/ https://www.ncbi.nlm.nih.gov/pubmed/34977046 http://dx.doi.org/10.3389/fcell.2021.812639 |
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