Design, Synthesis and Anti-Lung Cancer Evaluation of 1, 2, 3-Triazole Tethered Dihydroartemisinin-Isatin Hybrids

A series of 1,2,3-triazole tethered dihydroartemisinin-isatin hybrids 8a-c and 9a-k were designed and synthesized. Their antiproliferative activity against A549, doxorubicin-resistant A549 (A549/DOX) as well as cisplatin-resistant A549 (A549/DDP) lung cancer cell lines was also investigated in this...

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Detalles Bibliográficos
Autores principales: Hou, Haodong, Qu, Bin, Su, Chen, Hou, Guihua, Gao, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716824/
https://www.ncbi.nlm.nih.gov/pubmed/34975498
http://dx.doi.org/10.3389/fphar.2021.801580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716824/
https://www.ncbi.nlm.nih.gov/pubmed/34975498
http://dx.doi.org/10.3389/fphar.2021.801580

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