Identification of medicinal compounds as potential inhibitors for mutated isocitrate dehydrogenases against chondrosarcoma

Chondrosarcoma is the third most common cartilaginous bone tumour that is insusceptible to radio- and chemotherapy and it is inclined to metastasis. These resistant qualities are facilitated by mutant variants of isocitrate dehydrogenases (IDH) 1–2 enzyme. These mutant enzymes promote oncogenesis of...

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Detalles Bibliográficos
Autores principales: Shah, Fahad Hassan, Kim, Song Ja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716869/
https://www.ncbi.nlm.nih.gov/pubmed/35002404
http://dx.doi.org/10.1016/j.sjbs.2021.08.077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8716869/
https://www.ncbi.nlm.nih.gov/pubmed/35002404
http://dx.doi.org/10.1016/j.sjbs.2021.08.077

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