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Hepatitis B core antigen modulates exosomal miR-135a to target vesicle-associated membrane protein 2 promoting chemoresistance in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. The association of hepatitis B virus (HBV) infection with HCC is hitherto documented. Exosomal miRNAs contribute to cancer progression and chemoresistance. HBV X protein has been known to modulate miRNAs that faci...

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Detalles Bibliográficos
Autores principales: Wei, Xiao-Cui, Xia, Ya-Ru, Zhou, Ping, Xue, Xing, Ding, Shuang, Liu, Li-Juan, Zhu, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717014/
https://www.ncbi.nlm.nih.gov/pubmed/35068871
http://dx.doi.org/10.3748/wjg.v27.i48.8302