Cargando…

Dual therapy with zinc acetate and rifaximin prevents from ethanol-induced liver fibrosis by maintaining intestinal barrier integrity

BACKGROUND: Hepatic overload of gut-derived lipopolysaccharide dictates the progression of alcoholic liver disease (ALD) by inducing oxidative stress and activating Kupffer cells and hepatic stellate cells through toll-like receptor 4 signaling. Therefore, targeting the maintenance of intestinal bar...

Descripción completa

Detalles Bibliográficos
Autores principales: Fujimoto, Yuki, Kaji, Kosuke, Nishimura, Norihisa, Enomoto, Masahide, Murata, Koji, Takeda, Soichi, Takaya, Hiroaki, Kawaratani, Hideto, Moriya, Kei, Namisaki, Tadashi, Akahane, Takemi, Yoshiji, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717023/
https://www.ncbi.nlm.nih.gov/pubmed/35068872
http://dx.doi.org/10.3748/wjg.v27.i48.8323