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Dual therapy with zinc acetate and rifaximin prevents from ethanol-induced liver fibrosis by maintaining intestinal barrier integrity
BACKGROUND: Hepatic overload of gut-derived lipopolysaccharide dictates the progression of alcoholic liver disease (ALD) by inducing oxidative stress and activating Kupffer cells and hepatic stellate cells through toll-like receptor 4 signaling. Therefore, targeting the maintenance of intestinal bar...
Autores principales: | Fujimoto, Yuki, Kaji, Kosuke, Nishimura, Norihisa, Enomoto, Masahide, Murata, Koji, Takeda, Soichi, Takaya, Hiroaki, Kawaratani, Hideto, Moriya, Kei, Namisaki, Tadashi, Akahane, Takemi, Yoshiji, Hitoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717023/ https://www.ncbi.nlm.nih.gov/pubmed/35068872 http://dx.doi.org/10.3748/wjg.v27.i48.8323 |
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