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Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells

The efficacy of cisplatin (CDDP) has been demonstrated in the treatment of various cancers as monotherapy and combination therapy with immunotherapy. However, acquired CDDP resistance is a major obstacle to successful treatment. In the present study, the mechanisms underlying acquired CDDP resistanc...

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Detalles Bibliográficos
Autores principales: Horibe, Sayo, Ishikawa, Kaori, Nakada, Kazuto, Wake, Masaki, Takeda, Norihiko, Tanaka, Toru, Kawauchi, Shoji, Sasaki, Naoto, Rikitake, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717125/
https://www.ncbi.nlm.nih.gov/pubmed/34935060
http://dx.doi.org/10.3892/or.2021.8243