Glitter in the Darkness? Nonfibrillar β-Amyloid Plaque Components Significantly Impact the β-Amyloid PET Signal in Mouse Models of Alzheimer Disease

β-amyloid (Aβ) PET is an important tool for quantification of amyloidosis in the brain of suspected Alzheimer disease (AD) patients and transgenic AD mouse models. Despite the excellent correlation of Aβ PET with gold standard immunohistochemical assessments, the relative contributions of fibrillar...

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Detalles Bibliográficos
Autores principales: Biechele, Gloria, Monasor, Laura Sebastian, Wind, Karin, Blume, Tanja, Parhizkar, Samira, Arzberger, Thomas, Sacher, Christian, Beyer, Leonie, Eckenweber, Florian, Gildehaus, Franz-Josef, von Ungern-Sternberg, Barbara, Willem, Michael, Bartenstein, Peter, Cumming, Paul, Rominger, Axel, Herms, Jochen, Lichtenthaler, Stefan F., Haass, Christian, Tahirovic, Sabina, Brendel, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Basic Science Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717179/
https://www.ncbi.nlm.nih.gov/pubmed/34016733
http://dx.doi.org/10.2967/jnumed.120.261858

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717179/
https://www.ncbi.nlm.nih.gov/pubmed/34016733
http://dx.doi.org/10.2967/jnumed.120.261858

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