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Longitudinal Imaging of T Cells and Inflammatory Demyelination in a Preclinical Model of Multiple Sclerosis Using (18)F-FAraG PET and MRI

Lymphocytes and innate immune cells are key drivers of multiple sclerosis (MS) and are the main target of MS disease-modifying therapies (DMT). Ex vivo analyses of MS lesions have revealed cellular heterogeneity and variable T cell levels, which may have important implications for patient stratifica...

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Detalles Bibliográficos
Autores principales: Guglielmetti, Caroline, Levi, Jelena, Huynh, Tony L., Tiret, Brice, Blecha, Joseph, Tang, Ryan, VanBrocklin, Henry, Chaumeil, Myriam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717198/
https://www.ncbi.nlm.nih.gov/pubmed/33837066
http://dx.doi.org/10.2967/jnumed.120.259325