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Solution Structure and Conformational Flexibility of a Polyketide Synthase Module

[Image: see text] Polyketide synthases (PKSs) are versatile C–C bond-forming enzymes that are broadly distributed in bacteria and fungi. The polyketide compound family includes many clinically useful drugs such as the antibiotic erythromycin, the antineoplastic epothilone, and the cholesterol-loweri...

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Detalles Bibliográficos
Autores principales: Klaus, Maja, Rossini, Emanuele, Linden, Andreas, Paithankar, Karthik S., Zeug, Matthias, Ignatova, Zoya, Urlaub, Henning, Khosla, Chaitan, Köfinger, Jürgen, Hummer, Gerhard, Grininger, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717363/
https://www.ncbi.nlm.nih.gov/pubmed/34977887
http://dx.doi.org/10.1021/jacsau.1c00043