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Proteomic Analysis of Trichomonas vaginalis Phagolysosome, Lysosomal Targeting, and Unconventional Secretion of Cysteine Peptidases

The lysosome represents a central degradative compartment of eukaryote cells, yet little is known about the biogenesis and function of this organelle in parasitic protists. Whereas the mannose 6-phosphate (M6P)-dependent system is dominant for lysosomal targeting in metazoans, oligosaccharide-indepe...

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Detalles Bibliográficos
Autores principales: Zimmann, Nadine, Rada, Petr, Žárský, Vojtěch, Smutná, Tamara, Záhonová, Kristína, Dacks, Joel, Harant, Karel, Hrdý, Ivan, Tachezy, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717582/
https://www.ncbi.nlm.nih.gov/pubmed/34763061
http://dx.doi.org/10.1016/j.mcpro.2021.100174