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Dose of budesonide with surfactant affects lung and systemic inflammation after normal and injurious ventilation in preterm lambs

BACKGROUND: The addition of budesonide (Bud) 0.25 mg/kg to surfactant decreased the lung and systemic responses to mechanical ventilation in preterm sheep, and the rates and severity of bronchopulmonary dysplasia (BPD) in preterm infants. HYPOTHESIS: Lower budesonide concentrations in surfactant wil...

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Detalles Bibliográficos
Autores principales: Hillman, Noah H, Abugisisa, Leenah, Royse, Emily, Fee, Erin, Kemp, Matthew W, Kramer, Boris W, Schmidt, Augusto F, Salomone, Fabrizio, Clarke, Michael W, Musk, Gabrielle C, Jobe, Alan H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717708/
https://www.ncbi.nlm.nih.gov/pubmed/32066138
http://dx.doi.org/10.1038/s41390-020-0809-6