The Oxidation Cascade of a Rare Multifunctional P450 Enzyme Involved in Asperterpenoid A Biosynthesis

The cytochrome P450 enzymes (P450s or CYPs) are heme-containing enzymes which catalyze a wide range of oxidation reactions in nature. In our previous study, a rare multifunctional P450 AstB was found, which can dually oxidize two methyl groups (C-19 and C-21) of preasperterpenoid A to asperterpenoid...

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Detalles Bibliográficos
Autores principales: Huang, Hui-Yun, Huang, Jia-Hua, Wang, Yong-Heng, Hu, Dan, Lu, Yong-Jun, She, Zhi-Gang, Chen, Guo-Dong, Yao, Xin-Sheng, Gao, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717867/
https://www.ncbi.nlm.nih.gov/pubmed/34976952
http://dx.doi.org/10.3389/fchem.2021.785431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8717867/
https://www.ncbi.nlm.nih.gov/pubmed/34976952
http://dx.doi.org/10.3389/fchem.2021.785431

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