Cargando…

Decreased glutamate transport in acivicin resistant Leishmania tarentolae

Studies of drug resistance in the protozoan parasites of the genus Leishmania have been helpful in revealing biochemical pathways as potential drug targets. The chlorinated glutamine analogue acivicin has shown good activity against Leishmania cells and was shown to target several enzymes containing...

Descripción completa

Detalles Bibliográficos
Autores principales: Roy, Gaétan, Bhattacharya, Arijit, Leprohon, Philippe, Ouellette, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718007/
https://www.ncbi.nlm.nih.gov/pubmed/34914690
http://dx.doi.org/10.1371/journal.pntd.0010046