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Decreased glutamate transport in acivicin resistant Leishmania tarentolae
Studies of drug resistance in the protozoan parasites of the genus Leishmania have been helpful in revealing biochemical pathways as potential drug targets. The chlorinated glutamine analogue acivicin has shown good activity against Leishmania cells and was shown to target several enzymes containing...
Autores principales: | Roy, Gaétan, Bhattacharya, Arijit, Leprohon, Philippe, Ouellette, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718007/ https://www.ncbi.nlm.nih.gov/pubmed/34914690 http://dx.doi.org/10.1371/journal.pntd.0010046 |
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