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Validation and deployment of a direct saliva real-time RT-PCR test on pooled samples for COVID-19 surveillance testing

A direct, real-time reverse transcriptase PCR test on pooled saliva was validated in 2,786 participants against oropharyngeal swabs. Among asymptomatic/pre-symptomatic participants, the test was found to be in 99.21% agreement and 45% more sensitive than contemporaneous oropharyngeal swabs. The test...

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Detalles Bibliográficos
Autores principales: Rainey, Amanda, Pierce, Austin, Deng, Xiaoyun, Actis, Luis A., Smith, Philip, Kiss, Andor J., Wilson, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718011/
https://www.ncbi.nlm.nih.gov/pubmed/34969053
http://dx.doi.org/10.1371/journal.pone.0261956