RIPK3‐mediated cell death is involved in DUX4‐mediated toxicity in facioscapulohumeral dystrophy

BACKGROUND: Facioscapulohumeral dystrophy (FSHD) is caused by mutations leading to the aberrant expression of the DUX4 transcription factor in muscles. DUX4 was proposed to induce cell death, but the involvement of different death pathways is still discussed. A possible pro‐apoptotic role of DUX4 wa...

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Detalles Bibliográficos
Autores principales: Mariot, Virginie, Joubert, Romain, Le Gall, Laura, Sidlauskaite, Eva, Hourde, Christophe, Duddy, William, Voit, Thomas, Bencze, Maximilien, Dumonceaux, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718031/
https://www.ncbi.nlm.nih.gov/pubmed/34687171
http://dx.doi.org/10.1002/jcsm.12813

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718031/
https://www.ncbi.nlm.nih.gov/pubmed/34687171
http://dx.doi.org/10.1002/jcsm.12813

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