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Long‐term, induced expression of Hand2 in peripheral sympathetic neurons ameliorates sarcopenia in geriatric mice

BACKGROUND: The discovery of adrenoceptors, which mediate the effects of the sympathetic nervous system neurotransmitter norepinephrine on specific tissues, sparked the development of sympathomimetics that have profound influence on skeletal muscle mass. However, chronic administration has serious s...

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Detalles Bibliográficos
Autores principales: Rodrigues, Anna Carolina Zaia, Messi, María Laura, Wang, Zhong‐Min, Bonilla, Henry Jacob, Freeman, Willard M., Delbono, Osvaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718059/
https://www.ncbi.nlm.nih.gov/pubmed/34546662
http://dx.doi.org/10.1002/jcsm.12790