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Muscle mitochondrial catalase expression prevents neuromuscular junction disruption, atrophy, and weakness in a mouse model of accelerated sarcopenia

BACKGROUND: Oxidative stress and damage are associated with a number of ageing phenotypes, including age‐related loss of muscle mass and reduced contractile function (sarcopenia). Our group and others have reported loss of neuromuscular junction (NMJ) integrity and increased denervation as initiatin...

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Detalles Bibliográficos
Autores principales: Xu, Hongyang, Ranjit, Rojina, Richardson, Arlan, Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718066/
https://www.ncbi.nlm.nih.gov/pubmed/34559475
http://dx.doi.org/10.1002/jcsm.12768