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Glucose 6‐P dehydrogenase delays the onset of frailty by protecting against muscle damage

BACKGROUND: Frailty is a major age‐associated syndrome leading to disability. Oxidative damage plays a significant role in the promotion of frailty. The cellular antioxidant system relies on reduced nicotinamide adenine dinucleotide phosphate (NADPH) that is highly dependent on glucose 6‐P dehydroge...

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Detalles Bibliográficos
Autores principales: Arc‐Chagnaud, Coralie, Salvador‐Pascual, Andrea, Garcia‐Dominguez, Esther, Olaso‐Gonzalez, Gloria, Correas, Angela G., Serna, Eva, Brioche, Thomas, Chopard, Angele, Fernandez‐Marcos, Pablo J., Serrano, Manuel, Serrano, Antonio L., Muñoz‐Cánoves, Pura, Sebastiá, Vicente, Viña, Jose, Gomez‐Cabrera, Mari Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718080/
https://www.ncbi.nlm.nih.gov/pubmed/34704386
http://dx.doi.org/10.1002/jcsm.12792