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Determining the contributions of protein synthesis and breakdown to muscle atrophy requires non‐steady‐state equations
BACKGROUND: Ageing and cachexia cause a loss of muscle mass over time, indicating that protein breakdown exceeds protein synthesis. Deuterium oxide (D(2)O) is used for studies of protein turnover because of the advantages of long‐term labelling, but these methods introduce considerations that have b...
Autores principales: | Kobak, Kamil A., Lawrence, Marcus M., Pharaoh, Gavin, Borowik, Agnieszka K., Peelor, Frederick F., Shipman, Patrick D., Griffin, Timothy M., Van Remmen, Holly, Miller, Benjamin F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718081/ https://www.ncbi.nlm.nih.gov/pubmed/34418329 http://dx.doi.org/10.1002/jcsm.12772 |
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