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Loss of REDD1 prevents chemotherapy‐induced muscle atrophy and weakness in mice

BACKGROUND: Chemotherapy is an essential treatment to combat solid tumours and mitigate metastasis. Chemotherapy causes side effects including muscle wasting and weakness. Regulated in Development and DNA Damage Response 1 (REDD1) is a stress‐response protein that represses the mechanistic target of...

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Detalles Bibliográficos
Autores principales: Hain, Brian A., Xu, Haifang, Waning, David L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718092/
https://www.ncbi.nlm.nih.gov/pubmed/34664403
http://dx.doi.org/10.1002/jcsm.12795