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The Contribution of Astrocyte and Neuronal Panx1 to Seizures Is Model and Brain Region Dependent

Pannexin1 (Panx1) is an ATP release channel expressed in neurons and astrocytes that plays important roles in CNS physiology and pathology. Evidence for the involvement of Panx1 in seizures includes the reduction of epileptiform activity and ictal discharges following Panx1 channel blockade or delet...

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Detalles Bibliográficos
Autores principales: Obot, Price, Velíšek, Libor, Velíšková, Jana, Scemes, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718119/
https://www.ncbi.nlm.nih.gov/pubmed/33910381
http://dx.doi.org/10.1177/17590914211007273