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Clinical development of metabolic inhibitors for oncology

Metabolic inhibitors have been used in oncology for decades, dating back to antimetabolites developed in the 1940s. In the past 25 years, there has been increased recognition of metabolic derangements in tumor cells leading to a resurgence of interest in targeting metabolism. More recently there has...

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Detalles Bibliográficos
Autores principales: Lemberg, Kathryn M., Gori, Sadakatali S., Tsukamoto, Takashi, Rais, Rana, Slusher, Barbara S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718137/
https://www.ncbi.nlm.nih.gov/pubmed/34981784
http://dx.doi.org/10.1172/JCI148550