SIRT6 protects vascular smooth muscle cells from osteogenic transdifferentiation via Runx2 in chronic kidney disease

Vascular calcification (VC) is regarded as an important pathological change lacking effective treatment and associated with high mortality. Sirtuin 6 (SIRT6) is a member of the Sirtuin family, a class III histone deacetylase and a key epigenetic regulator. SIRT6 has a protective role in patients wit...

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Detalles Bibliográficos
Autores principales: Li, Wenxin, Feng, Weijing, Su, Xiaoyan, Luo, Dongling, Li, Zhibing, Zhou, Yongqiao, Zhu, Yongjun, Zhang, Mengbi, Chen, Jie, Liu, Baohua, Huang, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718147/
https://www.ncbi.nlm.nih.gov/pubmed/34793336
http://dx.doi.org/10.1172/JCI150051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718147/
https://www.ncbi.nlm.nih.gov/pubmed/34793336
http://dx.doi.org/10.1172/JCI150051

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