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A validated simple LC-MS/MS method for quantifying trimethylamine N-oxide (TMAO) using a surrogate matrix and its clinical application

Trimethylamine N-oxide (TMAO) is a small molecular amine oxide generated from dietary choline and carnitine through intestinal microbial metabolism. Recently, TMAO has attracted much public attention as its role in disease progression has been proven in many clinical studies. The plasma concentratio...

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Detalles Bibliográficos
Autores principales: Li, Yufei, Kang, Jihyun, Lee, Yujin, Chung, Jae-Yong, Cho, Joo-Youn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Clinical Pharmacology and Therapeutics 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718357/
https://www.ncbi.nlm.nih.gov/pubmed/35024362
http://dx.doi.org/10.12793/tcp.2021.29.e19