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Inhibition of Sphingosine-1-Phosphate Receptor 2 Prevents Thoracic Aortic Dissection and Rupture

Background: Numerous pieces of evidence have indicated that thoracic aortic dissection (TAD) is an inflammatory disease. Sphingosine-1-phosphate receptor 2 (S1PR2) signaling is a driver in multiple inflammatory diseases. Here, we examined the S1PR2 expression in TAD lesions and explored the effect o...

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Detalles Bibliográficos
Autores principales: Pan, Guangwei, Liao, Mengyang, Dai, Yong, Li, Yang, Yan, Xiaole, Mai, Wuqian, Liu, Jinping, Liao, Yuhua, Qiu, Zhihua, Zhou, Zihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718435/
https://www.ncbi.nlm.nih.gov/pubmed/34977175
http://dx.doi.org/10.3389/fcvm.2021.748486