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Randomised controlled trial to evaluate the effectiveness of using the RD-1-based C-Tb skin test as a replacement for blood-based interferon-γ release assay for detection of, and initiation of preventive treatment for, tuberculosis infection: RID-TB:Dx study protocol

INTRODUCTION: The predictive utility for incident tuberculosis (TB) of the purified protein derivative tuberculin skin test and region of difference 1 (RD1)-based interferon-gamma release assays (IGRA) is comparable; and either is recommended to test for latent TB infection (LTBI). Despite associate...

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Detalles Bibliográficos
Autores principales: Rangaka, Molebogeng X, Hamada, Yohhei, Duong, Trinh, Bern, Henry, Calvert, Joanna, Francis, Marie, Clarke, Amy Louise, Ghanouni, Alex, Hack, Vanessa, Owen-Powell, Ellen, Surey, Julian, Sanders, Karen, Booth, Helen L, Crook, Angela, Griffiths, Chris, Horne, Robert, Kunst, Heinke, Lipman, Marc, Mandelbaum, Mike, White, Peter J, Whiting, Penny, Zenner, Dominik, Abubakar, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718463/
http://dx.doi.org/10.1136/bmjopen-2021-050595