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CRF-receptor1 modulation of the dopamine projection to prelimbic cortex facilitates cognitive flexibility after acute and chronic stress

Stress reduces cognitive flexibility and dopamine D1 receptor-related activity in the prelimbic cortex (PL), effects hypothesized to depend on reduced corticotropic releasing factor receptor type 1 (CRFr1) regulation of dopamine neurons in the ventral tegmental area (VTA). We assessed this hypothesi...

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Detalles Bibliográficos
Autores principales: Mor, David, Becchi, Serena, Bowring, Jeremy, Tsoukalas, Madeline, Balleine, Bernard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718497/
https://www.ncbi.nlm.nih.gov/pubmed/35005102
http://dx.doi.org/10.1016/j.ynstr.2021.100424