Restrained expression of canine glucocorticoid receptor splice variants α and P prognosticates fatal disease outcome in SIRS

Glucocorticoids play a central role in the inflammatory response and alleviate the symptoms in critically ill patients. The glucocorticoid action relies on the glucocorticoid receptor (GR) which translocates into the nucleus upon ligand-binding and regulates transcription of a battery of genes. Alth...

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Detalles Bibliográficos
Autores principales: Kállai, Brigitta Margit, Csöndes, Judit, Kiss, Gergely, Bodrogi, Lilla, Rónai, Zsolt, Mészáros, Tamás
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718537/
https://www.ncbi.nlm.nih.gov/pubmed/34969952
http://dx.doi.org/10.1038/s41598-021-03451-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718537/
https://www.ncbi.nlm.nih.gov/pubmed/34969952
http://dx.doi.org/10.1038/s41598-021-03451-0

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