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Determination of tyrosinase-cyanidin-3-O-glucoside and (−/+)-catechin binding modes reveal mechanistic differences in tyrosinase inhibition

Tyrosinase, exquisitely catalyzes the phenolic compounds into brown or black pigment, inhibition is used as a treatment for dermatological or neurodegenerative disorders. Natural products, such as cyanidin-3-O-glucoside and (−/+)-catechin, are considered safe and non-toxic food additives in tyrosina...

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Detalles Bibliográficos
Autores principales: Lee, Kyung Eun, Bharadwaj, Shiv, Sahoo, Amaresh Kumar, Yadava, Umesh, Kang, Sang Gu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718538/
https://www.ncbi.nlm.nih.gov/pubmed/34969954
http://dx.doi.org/10.1038/s41598-021-03569-1