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Crystal Structures of Bat and Human Coronavirus ORF8 Protein Ig-Like Domain Provide Insights Into the Diversity of Immune Responses

ORF8 is a viral immunoglobulin-like (Ig-like) domain protein encoded by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA genome. It tends to evolve rapidly and interfere with immune responses. However, the structural characteristics of various coronavirus ORF8 proteins and their...

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Detalles Bibliográficos
Autores principales: Chen, Xiaoxue, Zhou, Zhechong, Huang, Chunliu, Zhou, Ziliang, Kang, Sisi, Huang, Zhaoxia, Jiang, Guanmin, Hong, Zhongsi, Chen, Qiuyue, Yang, Mei, He, Suhua, Liu, Siqi, Chen, Jie, Li, Kenan, Li, Xin, Liao, Jing, Chen, Jun, Chen, Shoudeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718552/
https://www.ncbi.nlm.nih.gov/pubmed/34975921
http://dx.doi.org/10.3389/fimmu.2021.807134