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Characterization of Glycosylation-Specific Systemic and Mucosal IgA Antibody Responses to Escherichia coli Mucinase YghJ (SslE)

Efforts to develop broadly protective vaccines against pathogenic Escherichia coli are ongoing. A potential antigen candidate for vaccine development is the metalloprotease YghJ, or SslE. YghJ is a conserved mucinase that is immunogenic, heavily glycosylated, and produced by most pathogenic E. coli....

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Detalles Bibliográficos
Autores principales: Riaz, Saman, Steinsland, Hans, Thorsing, Mette, Andersen, Ann Z., Boysen, Anders, Hanevik, Kurt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8718676/
https://www.ncbi.nlm.nih.gov/pubmed/34975849
http://dx.doi.org/10.3389/fimmu.2021.760135